Weight Uniformity Test of Divided Powders in Prescribing Pediatric Patients at Public Health Centers in Mataram

  • Yosi Agsanita Universitas Mataram
Keywords: Divided powders, pediatric patients, weight uniformity, public health center.

Abstract

Background : Weight uniformity becomes a determining factor in therapeutic success, which indicates the accuracy of drug dosage. One of the disadvantages of distributing divided powders preparations by the visual method is the non-uniformity of weightDivided powders are still prescribed for pediatric patients. The slight change in dosage can caused different effects in pediatric patients.

Objective : The purpose of this study was to determine the weight uniformity of divided powders in prescribing pediatric patients at 10 public health centers in Mataram.

Method :  This study was a descriptive research with a cross-sectional design. The sampling method used was non-probability sampling with a saturated sampling technique. The weight uniformity standard of divided powders follows Farmakope Indonesia III guidelines. Microsoft Excel 2010 software was used to analyze the data.

Results :  The maximum standard deviation of each 30 divided powders prepared in the morning and the afternoon were 107.75% and 70.17%, respectively.

Conclusion : All divided powders tested do not fulfill the requirements in the weight uniformity of divided powders according to the Farmakope Indonesia III standard because they had >15% of deviation.

References

1. Warnida, H., Sukawaty, Y., dan Aulya, M.A. Evaluasi Mutu Fisik Sediaan Pulveres pada Puskesmas di Kota Balikpapan. Jurnal Ilmu Kesehatan. 2018; 6(1).
2. Arianto, E. Sistem Takar Obat Serbuk (Puyer). Jurnal Penelitian. 2016; 19(2): 124-32.
3. Syamsuni. Farmasetika Dasar dan Hitungan Farmasi. Jakarta: Buku Kedokteran EGC, 2006.
4. Virginia, D.M. Peresepan Sediaan Racikan pada Pasien Anak di Bangsal Rawat Inap. Jurnal Penelitian. 2014; 18(1): 56-61.
5. Chiappini, E., Principi, N., and Longhi, R. Management of Fever in Children: Summary of the Italian Pediatric Society Guidelines. Clin Ther. 2009; 31(8): 1826-43.
6. Ben-Shachar, R., Chen, Y., Luo, S., Hartman, C., Reed, M., and Nijhout, H.F. The Biochemistry of Acetaminophen Hepatotoxicity and Rescue: A Mathematical Model. Theoretical Biology and Medical Modellin. 2012; 9(55): 11.
7. Sugianto, L., Yetti, O.K., dan Handayani, S. Uji Keseragaman Bobot dan Keseragaman Kadar Sediaan Pulveres yang Dibuat Apotek. Motorik. 2008; 3(6).
8. Rahayu, P., dan Yusrizal. Keseragaman Bobot Resep Racikan Serbuk Bagi (Pulveres) Di Apotek Kota Bandar Lampung Tahun 2017. Jurnal Analis Kesehatan. 2017; 8(1).
9. Departemen Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia No. 75 Tahun 2014 tentang Pusat Kesehatan Masyarakat. Departemen Kesehatan Republik Indonesia: Jakarta; 2014.
10. Departemen Kesehatan Republik Indonesia. Farmakope Indonesia Edisi Ketiga. Departemen Kesehatan Republik Indonesia: Jakarta; 1979.
11. Widyaswari, R., dan Wiedyaningsih, C. Evaluasi Profil Peresepan Obat Racikan dan Ketersediaan Formula Obat untuk Anak di Puskesmas Provinsi DIY. Majalah Farmaseutik. 2012; 8(3).
12. Badan Pusat Statistik Kota Mataram. Kota Mataram Dalam Data. Dinas Komunikasi dan Informatika Kota Mataram: Mataram; 2018.
13. Anief, M. Ilmu Meracik Obat. Gadjah Mada University Press: Yogyakarta; 2015.
14. Maharani, A.A.S.N., Pratama, K.M., Niruri, R., Dewantara, I G.N.A., Wati, K. D.K., dan Wiradotama, I G.B.G. Pengaruh Metode Pembagian Visual Dengan dan Tanpa Coating Terhadap Keseragaman Bobot Puyer Isoniazid Dosis Besar untuk Terapi Anak dengan HIV/AIDs-TB. Jurnal Farmasi Udayana. 2013.
Published
2021-12-09