Skin Microbioma and Role of Probiotics in Atopic Dermatitis
DOI:
https://doi.org/10.29303/jku.v11i1.519Keywords:
dermatitis atopik, disbiosis, mikrobioma, probiotikAbstract
Abstract
Atopic dermatitis (AD) is a multifactorial inflammatory skin disease that has a high prevalence globally. Many underlying factors can be the occurrence of AD, one of which is an imbalance in the composition and diversity of the microbiome in the skin and gut or it can be called a condition of dysbiosis. Management and prevention of dysbiosis can be a treatment strategy in AD. Various studies have been conducted to see the effectiveness of using biotic products, such as probiotics, in the management strategy of AD. Based on available scientific evidence, this review discusses skin microbiome and the role of probiotics in AD.
Keywords: atopic dermatitis, dysbiosis, microbiome, probiotic
1Medical Doctor Profession Education Program Faculty of Medicine University of Mataram
2Dermatovenereology Department, Faculty of Medicine University of Mataram / West Nusa Tenggara General Provincial Hospital
Email : sonyaaej@gmail.com
References
2. Bjerre RDD, Bandier J, Skov L, Engstrand L, Johansen JD. The role of the skin microbiome in atopic dermatitis : a systematic review. 2017;1272–8.
3. Knackstedt R, Knackstedt T, Gatherwright J. The role of topical probiotics in skin conditions : A systematic review of animal and human studies and implications for
12
future therapies. 2019;(29):15–21.
4. Chandrashekar BS, Agarwal R, Nayak PB. A 12 weeks , randomized and double-blind evaluation of the efficacy of oral supplements of probiotics ( Lactogut and Lactogut Kidz) on atopic dermatitis in adults and children. 2020;6(5):604–15.
5. Zhao M, Shen C, Ma L. Treatment efficacy of probiotics on atopic dermatitis, zooming in on infants : a systematic review and meta-analysis. Int J Dermatol. 2018;
6. Ibáñez MD, Rodríguez P, Alsina DG, Iglesias VV. Effect of synbiotic supplementation on children with atopic dermatitis : an observational prospective study. Eur J Pediatr. 2018;177:1851–8.
7. D’Auria E, Pilloni S, Beretta S, Paradiso L, Zuccotti G. Probiotics , Prebiotics and Postbiotics in Atopic Dermatitis. Biomed J Sci Tech Res. 2019;22(5).
8. Franca K. Topical Probiotics in Dermatological Therapy and Skincare : A Concise Review. 2021;71–7. 9. Marcinkowska M, Zagórska A, Fajkis N, Ko?aczkowski M, Pa?ko P. A Review of Probiotic Supplementation and Feasibility of Topical Application for the Treatment of Pediatric Atopic Dermatitis. Curr Pharm Biotechnol. 2018;19(10):827-838. 10. Huang R, Ning H, Shen M, Li J, Zhang J, Chen X. Probiotics for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Cell Infect Microbiol. 2017 Sep 6;7:392. doi: 10.3389/fcimb.2017.00392. PMID: 28932705; PMCID: PMC5592329.
11. Blanchet-Réthoré S, Bourdès V, Mercenier A, Haddar CH, Verhoeven PO, Andres P. Effect of a lotion containing the heat-treated probiotic strain Lactobacillus johnsonii NCC 533 on Staphylococcus aureus colonization in atopic dermatitis. Clin Cosmet Investig Dermatol. 2017;10:249–57.
12. Sumobaskoro A, Harsono G, Soebagyo B. Pengaruh Pemberian Probiotik pada Anak
13
dengan Dermatitis Atopik Terhadap Kadar Imunoglobulin E Total. Sari Pediatr. 2017;19(2):71.
13. Prameswari R, Astari L, Hidayati AN, Rosita C, Prakoeswa S. ARTIKEL ASLI Efek Lactobacillus plantarum terhadap Imunoglobulin E Serum Total dan Indeks Scoring Atopic Dermatitis (SCORAD) Pasien Dermatitis Atopik Anak (Effect of Lactobacillus plantarum on Total
Immunoglobulin E Serum and Scoring Atopic Dermatitis (SCORAD) Index in Children With Atopic Dermatitis). Berk Ilmu Kesehat Kulit dan Kelamin [Internet]. 2017;29(2):91–7. Available from: https://e-journal.unair.ac.id/BIKK/article/view/5558
14. Sholekhudin M. Buku Obat Sehari-hari. Elex Media Komputindo. 2014 hal. 84-85
