THE RELATIONSHIP BETWEEN DAILY INTAKE OF FOLIC ACID, VITAMIN B6, AND VITAMIN B12 AND ANKLE BRACHIAL INDEX PERIPHERAL ARTERY DISEASE PATIENTS IN MATARAM

  • Margian Tri Qurniadi Fakultas Kedokteran Universitas Mataram
  • Yanna Indrayana
  • Deasy Irawati
Keywords: Peripheral Artery Disease, Ankle Brachial Index, Folic Acid, Vitamin B6, and Vitamin B12

Abstract

Background: Peripheral Artery Disease (PAD) is partial to total blockage of blood vessels especially in the leg arteries. Ankle Brachial Index (ABI) can be used as a method of screening and diagnosis of PAD. Excess homocysteine is a risk factor of PAD. Deficiency of folic acid, vitamin B6, and vitamin B12 can disrupt homocysteine metabolism and increase the of PAD indirectly.

Method: This study is a cross sectional study conducted at Siti Hajar Islamic Hospital in Mataram. The sample was patients with peripheral artery disease with an ABI value <0,90. The number of research samples was 52. The sampling technique used consecutive sampling method. Data analysis used the Spearman correlation test.

Result: The average daily intake of folic acid, vitamin B6, and vitamin B12 in the study sample wass less than 50% of the recommended daily nutritional adequacy rate for Indonesians. The average ABI in the sample was 0,79. The results of the Spearman correlation test between ABI and folic acid intake showed a significance = 0,20 and coefficient correlation = 0,322. The results of the Spearman correlation test between the ABI and vitamin B6 intake showed a significance = 0,167. The results of the Spearman correlation test between ABI and vitamin B12 intake showed a significance = 0,800.

Conclusion: There is a significant relationship between ABI and folic acid intake. There is an insignificant relationship between ABI and vitamin B6 and vitamin B12.

Keywords: Peripheral Artery Disease, Ankle Brachial Index, Folic Acid, Vitamin B6, and Vitamin B12

References

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Published
2021-07-18