Evidence Based Case Study: Efektivitas Pemberian Vitamin D Selama Masa Perawatan pada Pasien Stroke
DOI:
https://doi.org/10.29303/jku.v12i4.1017Keywords:
Case study, Functional statue, Stroke, Vitamin DAbstract
Background /aim: The administration of vitamin D in stroke patients has been associated with functional improvement because it helps modify various cardiovascular risk factors. This study aimed to determine the effectiveness of vitamin D supplements to stroke patients.
Methods: The design of this study used an evidence-based case study approach conducted in July 2023 by including an illustration case study along with several supporting research studies to strengthen the findings. The research studies were collected through PubMed, Proquest, and ScienceDirect based on the PICO framework.
Results: Seven studies were included to support the finding of the illustration case study related to the effectiveness of vitamin D administration. The results of the studies showed that there were variations in the effects of giving a single dose of vitamin D or with a combination of other nutritional elements including helping to reduce serum levels of interleukin-1β (IL-1β) and interleukin 6 (IL-6), improving the patient's neurological function, and preventing the secondary hyperparathyroidism. The positive effects of giving vitamin D were also showed during the rehabilitation period of stroke patients including improving mood regulation and functional recovery as well as improving lower extremity motor function and ambulation.
Conclusion: The administration of vitamin D to stroke patients gives many positive contributions to both the acute and rehabilitation phases through various physiological mechanisms of the body. Health professionals are expected to consider adding vitamin D to a patient's nutritional care plan to achieve optimal health status outcomes.
References
Abdul, M., & Shahin, H. (2019). Ischemic Cerebral Stroke Case Report , Complications and Associated Factors. International Annals of Medicine, 1(February 2017). https://doi.org/10.24087/IAM.2017.1.2.49
Ashouri, R., Fangman, M., Brielmaier, J., Fields, Z. A., Campo, N., & Doré, S. (2021). Nutritional Supplementation of Naturally Occurring Vitamin D to Improve Hemorrhagic Stroke Outcomes. Frontiers in Neurology, 12(July), 1–9. https://doi.org/10.3389/fneur.2021.670245
Athanasiou, L. S., & Michalis, D. I. F. and L. K. (2017). Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging. Academic Press.
Azizieh, F., Alyahya, K. O., & Raghupathy, R. (2016). Association between levels of vitamin D and inflammatory markers in healthy women. Journal of Inflammation Research, 9, 51–57.
Bill, F., & Foundation, M. G. (2021). Articles Global , regional , and national burden of stroke and its risk factors , 1990 – 2019 : a systematic analysis for the Global Burden of Disease Study 2019. 20(October), 795–820. https://doi.org/10.1016/S1474-4422(21)00252-0
Coupland, A. P., Thapar, A., Qureshi, M. I., Jenkins, H., & Davies, A. H. (2017). The definition of stroke. Journal of the Royal Society of Medicine, 110(1), 9–12. https://doi.org/10.1177/0141076816680121
Gupta, A., Prabhakar, S., Modi, M., Bhadada, S. K., Kalaivani, M., Lal, V., & Khurana, D. (2016). Effect of Vitamin D and calcium supplementation on ischaemic stroke outcome : a randomised controlled open- label trial. The International Journal of Clinical Practice, June, 1–7. https://doi.org/10.1111/ijcp.12866
Hastalarında, İ., Yaklaşım, N., Görüşü, U., Güngör, L., Işıkay, C. T., & Yaka, E. (2018). Nutritional Approach and Treatment in Patients with Stroke , An Expert Opinion for Turkey. Turkish Journal of Neurology, 14, 226–242.
Hesami, O., Iranshahi, S., Shahamati, S. Z., Sistanizd, M., Pourheidar, E., & Hassanpour, R. (2022). The Evaluation of the Neuroprotective Effect of a Single High- Dose Vitamin D 3 in Patients with Moderate Ischemic Stroke. Stroke Research and Treatment, 1–6.
Kadri, A., Sjahrir, H., Sembiring, R. J., & Ichwan, M. (2020). Combination of vitamin A and D supplementation for ischemic stroke : effects on interleukin-1ß and clinical outcome. Medicinski Glasnik, 17(May), 425–432. https://doi.org/10.17392/1137-20
Karasu, A. U., & Karataş, G. K. (2021). Effect of vitamin D supplementation on lower extremity motor function and ambulation in stroke patients. Turkish Journal of Medical Sciences, 51, 1413–1419. https://doi.org/10.3906/sag-2010-287
Kartika, G., Amalia, L., & Nugraha, G. I. (2017). Nutritional Status of Hospitalized Stroke Patients : Assessment by Body Mass Index and Subjective Global Assessment Method. Althea Medical Journal, 4(2), 293–298.
Kementerian Kesehatan RI. (2018). Laporan Nasional Riskesdas 2018. Badan Penelitian dan Pengembangan Kesehatan.
Kiggundu, D. S., Mutebi, E., Kibirige, D., Boxer, R., Kakande, B., Kigozi, B. K., & Katabira, E. (2015). Vitamin D deficiency and its characteristics among patients with acute stroke at a national referral hospital in Kampala Uganda. BMC Endocrine Disorders, 53, 1–8. https://doi.org/10.1186/s12902-015-0053-y
Lu, H.-Y., Ho, U.-C., & Kuo, L.-T. (2023). Impact of Nutritional Status on Outcomes of Stroke Survivors : A Post Hoc Analysis of the NHANES. Nutrients, 15(294), 1–16.
Narasimhan, S., & Balasubramanian, P. (2017). Role of Vitamin D in the Outcome of Ischemic Stroke- A Randomized Controlled Trial. Journal of Clinical and Diagnostic Research, 11(2), 6–10. https://doi.org/10.7860/JCDR/2017/24299.9346
Pu, L., Wang, L., Zhang, R., Zhao, T., Jiang, Y., & Han, L. (2023). Projected Global Trends in Ischemic Stroke Incidence , Deaths and Disability-Adjusted Life. Stroke, May, 1330–1339. https://doi.org/10.1161/STROKEAHA.122.040073
Rezaei, O., Ramezani, M., Roozbeh, M., Fazeli, B., Hajiesmaeili, M., Pakdaman, H., & Simani, L. (2021). Does vitamin D administration play a role in outcome of patients with acute ischemic stroke ? A randomized controlled trial. Current Journal of Neurology, 20(1), 8–14.
Shoaib, A., & Børge G, N. (2017). Vitamin D, Hypertension, and Ischemic Stroke in 116 655 Individuals From the General Population. Hypertension, 70(3), 499–507. https://doi.org/10.1161/HYPERTENSIONAHA.117.09411
Torrisi, M., Psy, D., Bonanno, L., Formica, C., Psy, D., Arcadi, F. A., Cardile, D., Psy, D., Cimino, V., Bramanti, P., & Morini, E. (2021). The role of rehabilitation and vitamin D supplementation on motor and psychological outcomes in poststroke patients. Medicine, 100(45).
Turetsky, A., Goddeau, R. P., & Henninger, N. (2015). Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases, 24(7), 1555–1563. https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.03.051
Wirth, R., Smoliner, C., Jäger, M., Warnecke, T., Leischker, A. H., & Dziewas, R. (2013). Guideline clinical nutrition in patients with stroke. Experimental & Translational Stroke Medicine, 5(14), 1–11.
World World Stroke Organization. (2022). Global Stroke Fact Sheet 2022. https://www.world-stroke.org/assets/downloads/WSO_Global_Stroke_Fact_Sheet.pdf
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Jurnal Kedokteran
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
