NARKOLEPSI: PATOFISIOLOGI, DIAGNOSIS DAN MANAJEMEN
DOI:
https://doi.org/10.29303/jku.v9i1.401Kata Kunci:
Narkolepsi, Cataplexy, Gangguan Tidur, KomorbiditasAbstrak
Narkolepsi telah dikenal lama oleh profesi medis. Narkolepsi sangat mengganggu karena tidur dan bangun menjadi tidak teratur. Cataplexy adalah sebuah gejala yang paling sering dikaitkan dengan narkolepsi, meski ada banyak gejala lainnya yang menyertai penyakit gangguan tidur.
Narkolepsi dengan cataplexy (tipe 1) bisa langsung didiagnosis. Diagnosa narkolepsi tanpa cataplexy (tipe 2) sering sulit karena hasil diagnosanya perlu diuji dan batasannya pun perlu dipahami. Narkolepsi sering dianggap pemicu terjadinya komorbiditas multipel.
Referensi
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7. Naumann A, Daum I. Narcolepsy: Pathophysiology and neuropsychological changes. Behavioural Neurology 14 (2003) 89–98.
8. Overeem S, Reading P.(2010). Sleep disorder in Neurology A Practical Approach. Singapore. Blackwell Publishing Ltd
9. Somers, E. C., Thomas, S. L., Smeeth, L. and Hall, A. J. Are individuals wtih an autoimmune disease at higher risk of a second autoimmune disorder? Am. J. Epidemiol., 2009, 169: 749–755.
10. Bonvalet M, Ollila HM, Ambati A, Mignot E. Autoimmunity in narcolepsy. Curr Opin Pulm Med 2017, 23:522–529.
11. Burgess CR, Scammel TE. Narcolepsy: Neural Mechanisms of Sleepiness and Cataplexy. The Journal of Neuroscience, September 5, 2012;32(36):12305–12311
12. Chokroverty S, Bhat S. (2017). Oxford Textbook Of Sleep Disorders. Oxford Textbooks in Clinical Neurology. Oxford University Press. United Kingdom.
13. Fortuyn HAD, Fronczek R, Smitshoek M, Overeem S, et al. Severe fatigue in narcolepsy with cataplexy. J. Sleep Res. (2012) 21, 163–169.
14. Jacobson, D. L., Gange, S. J. and Rose, N. R. and Graham N. M. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin. Immunol. Immunopathol., 1997, 84: 223–243.
15. Kryger M, Roth T, Dement WC. (2017). Principles and practice of sleep medicine, sixth edition. Philadelphia: Elsevier Inc.
16. Martinez-Orozco FJ, Vicario JL, Villalibre-Valderrey I, Andres CD, et al. Narcolepsy with cataplexy and comorbid immunopathological diseases. J Sleep Res. (2014) 23, 414–419.
17. Meyer C, Junior GJF, Barbarosa DG, et al. Analysis of daytime sleepiniess in adolescents by the pediatric daytime sleepiness scale: A systemic review. Rev Paul Pediatr. 2017;35(3):351-360. http://dx.doi.org/10.1590/1984 0462/;2017;35;3;00015
18. Morandin M, Bruck D. Understanding Automatic Behavior in Narcolepsy: New Insights Using a Phenomenological Approach. The Open Sleep Journal, 2013, 6, 1-7.
19. Neppe VM. Revisiting Narcolepsy: The Practical Diagnosis and Mythology. J Psychol Clin Psychiatry 2016, 5(3): 00287.
20. Peacock J, Benca RM. Narcolepsy: Clinical features, co-morbidities & treatment. Indian J Med Res 131, February 2010, pp 338-349.
21. Perez-Chada, D., Perez-Lloret, S., Videla, A. J., Cardinali, D., Bergna, M. A., Fernández-Acquier, et al. (2007). Sleep Disordered Breathing And Daytime Sleepiness Are Associated With Poor Academic Performance In Teenagers. A Study Using The Pediatric Daytime Sleepiness Scale (PDSS). Sleep, 30(12), 1698–1703.
22. Peplow Mark. (2013). The Anatomy of Sleep. Nature Volume 497 issue 7450. Macmillan Publisher Limited.
23. Rahman T, Farook O, Heyat Md BB, Siddiqui MM. (2016). An Overview of Narcolepsy. International Advanced Research Journal in Science, Engineering and Technology. (Vol. 3).
24. Somers, E. C., Thomas, S. L., Smeeth, L. and Hall, A. J. Autoimmune diseases co-ocurring within individuals and within families. Epidemiology, 2006, 17: 202–217.
25. Zee PC, Hammond RC. (2007). Review of Sleep Medicine Second Edition. Elsevier. Philadelphia
2. Ropper AH, Samuels MA, Klein JP.(2014). Adams and Victor`s Principles of Neurology Tenth Editions. McGraw-Hill Education.
3. Purnomo Hari. (2014). Panduan Tatalaksana Gangguan Tidur Edisi 1. Kelompok Studi Gangguan Tidur Perhimpunan Dokter Spesialis Saraf (PERDOSSI). Surabaya.
4. Mignot, E. (2017). Narcolepsy: Genetics, Immunology, and Pathophysiology. Kryger, M., Roth T.,Dement W.C. Principles and Practice of Sleep Medicine. Sixth Edition. Philadelphia: Elsevier.
5. Scammell TE. Narcolepsy. N Engl J Med 2015;373:2654-62. http:// DOI: 10.1056/ NEJMra1500587.
6. Cao, M.T., Guilleminault, C. (2017). Narcolepsy: Diagnosis and Management. Kryger, M., Roth T.,Dement W.C. Principles and Practice of Sleep Medicine. Sixth Edition. Philadelphia: Elsevier.
7. Naumann A, Daum I. Narcolepsy: Pathophysiology and neuropsychological changes. Behavioural Neurology 14 (2003) 89–98.
8. Overeem S, Reading P.(2010). Sleep disorder in Neurology A Practical Approach. Singapore. Blackwell Publishing Ltd
9. Somers, E. C., Thomas, S. L., Smeeth, L. and Hall, A. J. Are individuals wtih an autoimmune disease at higher risk of a second autoimmune disorder? Am. J. Epidemiol., 2009, 169: 749–755.
10. Bonvalet M, Ollila HM, Ambati A, Mignot E. Autoimmunity in narcolepsy. Curr Opin Pulm Med 2017, 23:522–529.
11. Burgess CR, Scammel TE. Narcolepsy: Neural Mechanisms of Sleepiness and Cataplexy. The Journal of Neuroscience, September 5, 2012;32(36):12305–12311
12. Chokroverty S, Bhat S. (2017). Oxford Textbook Of Sleep Disorders. Oxford Textbooks in Clinical Neurology. Oxford University Press. United Kingdom.
13. Fortuyn HAD, Fronczek R, Smitshoek M, Overeem S, et al. Severe fatigue in narcolepsy with cataplexy. J. Sleep Res. (2012) 21, 163–169.
14. Jacobson, D. L., Gange, S. J. and Rose, N. R. and Graham N. M. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin. Immunol. Immunopathol., 1997, 84: 223–243.
15. Kryger M, Roth T, Dement WC. (2017). Principles and practice of sleep medicine, sixth edition. Philadelphia: Elsevier Inc.
16. Martinez-Orozco FJ, Vicario JL, Villalibre-Valderrey I, Andres CD, et al. Narcolepsy with cataplexy and comorbid immunopathological diseases. J Sleep Res. (2014) 23, 414–419.
17. Meyer C, Junior GJF, Barbarosa DG, et al. Analysis of daytime sleepiniess in adolescents by the pediatric daytime sleepiness scale: A systemic review. Rev Paul Pediatr. 2017;35(3):351-360. http://dx.doi.org/10.1590/1984 0462/;2017;35;3;00015
18. Morandin M, Bruck D. Understanding Automatic Behavior in Narcolepsy: New Insights Using a Phenomenological Approach. The Open Sleep Journal, 2013, 6, 1-7.
19. Neppe VM. Revisiting Narcolepsy: The Practical Diagnosis and Mythology. J Psychol Clin Psychiatry 2016, 5(3): 00287.
20. Peacock J, Benca RM. Narcolepsy: Clinical features, co-morbidities & treatment. Indian J Med Res 131, February 2010, pp 338-349.
21. Perez-Chada, D., Perez-Lloret, S., Videla, A. J., Cardinali, D., Bergna, M. A., Fernández-Acquier, et al. (2007). Sleep Disordered Breathing And Daytime Sleepiness Are Associated With Poor Academic Performance In Teenagers. A Study Using The Pediatric Daytime Sleepiness Scale (PDSS). Sleep, 30(12), 1698–1703.
22. Peplow Mark. (2013). The Anatomy of Sleep. Nature Volume 497 issue 7450. Macmillan Publisher Limited.
23. Rahman T, Farook O, Heyat Md BB, Siddiqui MM. (2016). An Overview of Narcolepsy. International Advanced Research Journal in Science, Engineering and Technology. (Vol. 3).
24. Somers, E. C., Thomas, S. L., Smeeth, L. and Hall, A. J. Autoimmune diseases co-ocurring within individuals and within families. Epidemiology, 2006, 17: 202–217.
25. Zee PC, Hammond RC. (2007). Review of Sleep Medicine Second Edition. Elsevier. Philadelphia
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2020-05-10
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sahidu, ghalvan, & Afif, Z. . (2020). NARKOLEPSI: PATOFISIOLOGI, DIAGNOSIS DAN MANAJEMEN. Baphomet University : Situs Slot Online Gacor Terbaik Hari Ini Server Thailand Gampang Maxwin 2024, 9(1), 1–12. https://doi.org/10.29303/jku.v9i1.401
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