Tatalaksana Non-Acetaminophen Induced Acute Liver Failure Dengan Menggunakan N-acetylcysteine
DOI:
https://doi.org/10.29303/jku.v11i4.801Kata Kunci:
N-acetylcysteine, Non-Acetaminophen Induced Acute Liver FailureAbstrak
Gagal hati akut merupakan suatu kondisi dimana terjadi disfungsi hati yang akut. Terdapat dua jenis akut dari gagal hati akut ini yaitu acetaminophen induced acute liver failure dan non acetaminophen induced acute liver failure.Gagal hati memiliki penilaian angka insidensi sebanyak 1-6 kasus per 1 juta setiap tahun pada berbagai negara maju, sedangkan untuk Negara berkembang angka insidensi diperkiraan lebih besar karena memiliki angka insidensi hepatitis yang tinggi, di Amerika, diperkirakan sebanyak 2.500 kasus gagal hati akut per tahun. Sampai saat ini, tidak ada pengobatan yang mampu untuk gagal hati akut yang disebabkan oleh non-acetaminophenselain dengan cara transplantasi hati. hasil analisis penelitian yang dilakukan, terapi pengobatan N-acetylcysteine ??(NAC) pada gagal hati akut yang diinduksi non-acetaminopen dapat Berdasarkan yang dijanjikan. Non-acetaminophen induced acute liver failure dengan meningkatkan hemodinamik sistemik dan penghantaran oksigen ke jaringan.
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