Psychotropic Drugs Use in Asthmatic Children and Adolescents in The Netherlands 1999-2006
DOI:
https://doi.org/10.29303/jku.v1i1.43Abstract
Introduction: To determine the association between asthma and the use of psychotropic drugs by focusing on whether the asthmatic children receive more often psychotropic drugs compared with non asthmatic children in the population based cohort design.
Method: Using InterAction Database (IADB), drug dispensing data from Dutch community pharmacies (55 community pharmacies) in 1999 – 2006, children and adolescents aged 0 to 19 years in the study period (1 Januari 1999 to 31 Desember 2006 were divided into two groups; the index (asthmatic children and adolescents) and the reference (antibiotic children and adolescents) groups. We calculated the incidences of psychotropic drugs use (in both groups) and the incidence risk ratio (IRR).
Results: The incidences of psychotropic drug use were 0.058 cases/1000 person-days in index group and 0.048 cases/1000 person-days in reference group. The incidence risk ratio of anti psychotropic drug use was 1.21 ( CI 1.18-1.29).
Conclusions : Asthmatic patients are 1.21 times more likely than non asthmatic patients to receive psychotropic drugs over the 8 years period in this study.
References
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19. Schirm E, Tobi H, Zito JM, Berg LT De Jong-van den: Psychotropic medication in children: a study from the Netherlands. Pediatrics2001, 108:e25.
20. Tjalling de Vries, 2008, Improving Care in Paediatric Asthma : Patients, Prescription, Pharmacovigilance, Pathogens, and Particles, Thesis, Groningen University
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24. www.ginasthma.org
25. http://www.iadb.nl/downloads/2009/josta_2009.pdf
2. Azorin JM, Findling RL. Valproate Use in children and adolescents with bipolar disorder.CNS Drugs. 2007: 21 (12): 1019-33.
3. Bender BG, Annett RD, Ikle D, DuHamel TR, Rand C, Strunk RC, Relationship between disease and psychological adaptation in children in the Childhood Asthma Management Program and their families. Arch Pediatr Adolesc Med(2000) 154:706–713
4. Debarr LL, Lynch F, Powell J, Gale J. Use of psychotropic agents in preschool children: associated symptoms, diagnoses and health care services in a health maintenance organization. Arch Pediatr Adolesc Med 2003;157:150-157
5. T. W. de Vries . J. J. de LangenWouterse . E. van Puijenbroek . E. J. Duiverman . L. T. W. de Jong-Van den Berg ,Reported adverse drug reactions during the use of inhaled steroids in children with asthma in the Netherlands, Springer-Verlag 2006
6. Fegert JM, Kolch M, Zito JM, Glaeske G, Janhsen K: Antidepressant use in children and adolescents in Germany. J Child Adolesc Psychopharmacol 2006, 16:197-206
7. Garlehner G, Hansen RA, Kahwati L. Second generation antidepressants: DERP Review. September 2006 8. Goodwin RD, Eaton WW. Asthma and the risk of panic attacks among adults in the community. Psychol Med 2003;33(5):879-885.
9. Hoekstra.et.al, Antiepileptic drug utilization in children from 1997–2005—a study from the Netherlands, Eur J Clin Pharmacol, DOI 10.1007/s00228-008-0480-z,2008
10. Hugtenburg JG, Heerdink ER, Egberts ACG: Increased psychotropic drug consumption by children in the Netherlands during 1995–2001 is caused by increased use of methylphenidate by boys. Eur J Clin Pharmacol 2004, 60:377-379.
11. Klein DF. False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis.Arch Gen Psychiatry 1993;50(4):306-317.
12. Mauro Percudani et.al, Worrying patterns of out patient psychotropic drug prescribing in children and adolescents, Psychother Psychosom 2005, 74:189-190
13. McQuaid, E. L., Kopel, S. J. & Nassau, J. H. (2001) Behavioral adjustment in children with asthma: a metaanalysis. Journal of Developmentaland BehavioralPediatrics 22, 430–439.
14. Mongeluzi DL, Rosellini RA, Ley R, Caldarone BJ, Stock HS. The conditioning of dyspneic suffocation fear. Effects of carbon dioxide concentration on behavioral freezing and analgesia. Behav Modif 2003;27(5):620-636
15. Murray ML, de Vries CS, Wong ICK: A drug utilisation study of antidepressants in children and adolescents using the General Practice Research Database. Arch Dis Child 2004, 89:1098-1102
16. Ortega et.al, 2002, Childhood Asthma, Chronic Illness, and Psychiatric Disorder, Journal of Nervous and Mental Disorder, 190, 275-281
17. Riddle MA, Kastelic EA, Frosch E. Pediatric Psychopharmacology. J. Child Psychol. Psychiat. 2001;vol 42(1): 73-90
18. Schirm E, Monster TBM, de Vries R, van den Berg PB, de Jongvan den Berg LTW, Tobi H (2004) How to estimate the population that is covered by community pharmacies? An evaluation of two methods using drug utilisation information. Pharmacoepidemiol Drug Saf 13:173–179
19. Schirm E, Tobi H, Zito JM, Berg LT De Jong-van den: Psychotropic medication in children: a study from the Netherlands. Pediatrics2001, 108:e25.
20. Tjalling de Vries, 2008, Improving Care in Paediatric Asthma : Patients, Prescription, Pharmacovigilance, Pathogens, and Particles, Thesis, Groningen University
21. Vila G., Nollet-Clemencon C., Blic J. De., Falissard B., Mouren-Simeoni M., Scheinmann P. Assessment of Anxiety Disorders in Asthmatic Children. Psychosomatics 1999; 40: 404-413
22. Wamboldt MZ, Fritz G, Mansell A, McQuaid EL, Klein RB, Relationship of asthma severity and psychological problems in children. J Am Acad Child Adolesc Psychiatry (1998) 37:943–950.
23. Zito.et.al, A three-country comparison of psychotropic medication prevalence in youth, Child and Adolescent Psychiatry and Mental Health, Child and Adolescent Psychiatry and Mental Health 2008, 2:26 doi:10.1186/1753-2000-2-26
24. www.ginasthma.org
25. http://www.iadb.nl/downloads/2009/josta_2009.pdf
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Published
2017-10-23
How to Cite
Aini, S. R. (2017). Psychotropic Drugs Use in Asthmatic Children and Adolescents in The Netherlands 1999-2006. Jurnal Kedokteran, 1(1). https://doi.org/10.29303/jku.v1i1.43
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