Diverticulosis and Diverticulitis
A Rarely Known Anatomical Changes of The Colon
Keywords:divertikulitis; diverkulosis; klasifikasi; patofisiologi; diagnosis; penatalaksanaan
Diverticulitis is a gastrointestinal anatomical changes that usually happens in the colon wall. This condition happens in 10-25% in patients with diverticulosis. The classification of the disease can be divided into acute, chronic, complicated, and uncomplicated. Diverticulitis happens commonly in men than women. The pathophysiology of diverticulitis is when the diverticula of the colon become inflamed. Inflammation of the diverticula happens when a small and hard feces pass through the large intestine. People with diverticulitis usually experience intermittent abdominal pain in the left lower quadrant. However, the abdominal pain can also occur in the right lower quadrant based on diverticulitis in Asian population. Constipation and diarrhea also often happen. Subsequently, on physical evaluation tenderness to palpation in the inflamed quadrant of the abdomen. Diverticulitis can be diagnosed clinically based on history and physical examination. However, the result can be inaccurate in 24-68% of cases because the clinical manifestations may be similar to other differential diagnoses. Therefore, laboratory and radiological tests are really important to show an accurate result. Laboratory test commonly finds leukocytosis, elevation in erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The radiological choice to diagnose diverticulitis are CT scan of the abdomen and pelvis, USG, and MRI. Management for diverticulitis without complication is antibiotic therapy. Meanwhile if the antibiotic therapy cannot cope with the diverticulitis, surgery may be performed.
Talutis SD, Kuhnen FAH. Pathophysiology and Epidemiology of Diverticular Disease. Clin Colon Rectal Surg. 2021;34(2):81–5.
Imaeda H, Hibi T. The Burden of Diverticular Disease and Its Complications: West versus East. Inflamm Intest Dis. 2018;3(2):61–8.
Strate LL, Morris AM. Epidemiology, Pathophysiology, and Treatment of Diverticulitis. Gastroenterology. 2019;156(5):1282-1298.e1.
Lembcke B. Diagnosis, differential diagnoses, and classification of diverticular disease. Visz Gastrointest Med Surg [Internet]. 2015;31(2):95–102. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789974/
Rezapour M, Ali S, Stollman N. Diverticular disease: An update on pathogenesis and management. Gut Liver. 2018;12(2):125–32.
Nallapeta NS, Farooq U, Patel K. Diverticulosis. 2022; Available from: https://www.ncbi.nlm.nih.gov/books/NBK430771/
P B. DIET PADA PENYAKIT DIVERTIKULITIS Diet in Diverticulitis Disease Bondan P Staf Pengajar Universitas Muhammadiyah. JNH (Journal Nutr Heal. 2021;9(1):39–43.
Elisei W, Tursi A. The Pathophysiology of Colonic Diverticulosis: Inflammation versus Constipation? Inflamm Intest Dis. 2018;3(2):55–60.
Linzay CD, Pandit S. Acute Diverticulitis. StatPearls Publ. 2021;400–4.
NICE. Diverticular disease: diagnosis and management. NICE Guidel Publ 27 Novemb 2019. 2019;85(November).
Swanson SM, Strate LL. Acute colonic diverticulitis. Ann Intern Med. 2018;168(9):ITC65–79.
Wilkins T, Embry K, George R. Diagnosis and management of acute Diverticulitis. Am Fam Physician. 2013;87(9):612–20.
Dwiyanti DAA, Suputra PA. Diet Divertikulitis. Ganesha Med. 2021;1(1):1.
You H, Sweeny A, Cooper ML, Von Papen M, Innes J. The management of diverticulitis: a review of the guidelines. Med J Aust. 2019;211(9):421–7.
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