EFEKTIVITAS PETIDIN 25 MG INTRAVENA UNTUK MENCEGAH MENGGIGIL PASCA ANESTESI UMUM
DOI:
https://doi.org/10.29303/jku.v2i3.67Abstract
Background : Post anesthesia complication scan be caused by various factors, shivering is quite frequently encountered complications during recovering time. Risks that may happen is increasing of metabolism and make post operative pain worst. This study proves petidine can be used as an alternative to prevent shivering after general anesthesia. Methods : This research includes phase II clinical trials, the sample selection by Quota Sampling of patients are being prepared for elective surgery with general anesthesia, aged 20-40 years, ASA I-II, all patients who meet the criteria for inclusion in the sample until the required number met, willing to volunteer. Randomization was done at the end of the operation. Patients were divided into two groups, Pand S.Severity of shivering were recorded and assessed. Results : Characteristics of patients five minutes before induction did not significant differences. Measurement of systolic blood pressure and heart rate immediately after extubation showed significant differences. Duration of shivering in saline group occurredin almost the same when compared with the treatment group, because after the shivering, the patient is given immediate intervention of meperidine of 25mg for the treatment of shivering occurred, especially given to people who experience shivering with2nd, 3rd, or 4th degree. For patients shivered first degree was given meperidine administration intervention. Duration of shivering in the control group took place in almost the same time. Conclusion : Pethidine had a good effectiveness in preventing the occurrence of shivering after general anesthesia. Keywords: Pethidine, shivering after general anesthesia.References
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Anaesthesiologica Scandinavia 1995 ; 39 (1):90–5.
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2000 ; 57 : 387 – 95.
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Postanesthetic shivering. Anaesthesia 2002;65 : 578 – 83.
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Pharmacology and physiology in anesthetic practice. 3rd ed. Philadelphia :
JB Lippincott Company 1999 : 82 – 4.
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Physiologic and pharmacologic bases of anesthesia. Baltimore : William & Wilkins, 1996 : 582 –3.
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21. Akinci. B, Basgul. E, Aypar. U. Pharmacological modulation of
shivering.Br. J. Anaesth. 1997: 613 – 7.
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Ismael S, eds. Dasar-dasar metodologi penelitian klinis edisi 2. Jakarta : Sagung Seto, 2002 : 67 – 77.
Morgan GE, Mikhail MS, Murray MJ, Larson CP. Clinical Anesthesiology.
4thed. New York : Lange Medical Books/McGraw-Hill Medical Publishing
Edition, 2006 : 169 – 72.
2. Tsai YC, Chu KS. Anesthetic shivering in parturients. Anesth Analg 2001 ; 93:1288 – 92.
3. Schawarzkopt KR, Hoft H, Hartman M, Fritz HG. Treatment of postanesthetic shivering. Anesth Analg 2001 ; 95:257 – 60.
4. Piper Sn, Maleck WH, Bolt J, Suttner SW, Schmidt CC, Reich DGP. Preventing postanesthetic shivering. Anesth Analg 2000 ; 90:954 – 7.
5. Bigatella L. The post anesthesia care unit. In : Davidson JK, Eckhart WT,
Perese DA, eds. Cinical anesthesia procedures of the massachusetts general
hospital, 4th ed. Boston : Little Broun and Co, 1993 : 527 – 43.
6. Horn EP. Physostigmin prevents post anesthetic shivering as does meperidine or clonidine. Anesthesiology, 1998 ; 88 : 108 – 13.
7. Wang JJ, Ho ST, Lu SC, Liu YC. Treating postanesthetic shivering. Anesth Analg 1999 ; 88:686 – 9.
8. Behringer EC. Postanesthesia care. In : Longnecker DE., Murphy FL (eds).
Introduction to anesthesia. Philadelphia : W.B. Saunders Company, 1997 : 438-9.
9. De Witte J., Sessler. D. Perioperative shivering: Physiology and Pharmacology. American Society of Anesthesiologists 2002; 96 : 467 – 84.
10. Rosa G, Pinto G, Orsi P. Control of post anesthetic shivering. Acta
Anaesthesiologica Scandinavia 1995 ; 39 (1):90–5.
11. Chan AMH, Ng KFJ, Tong EWN, Jan GSK. Control of shivering under general anesthesia. Can J Anesth 1999; 46: 253 – 8.
12. Mathews S., Varghese PK,. Postanesthetic shivering. Anaesthesia
2000 ; 57 : 387 – 95.
13. Bhatnagar S., Kannan TR., Panigrahi M. Pethidine for Post operative shivering. Anaesthesia and Intensive Care 2002 ; 32 : 294 – 305.
14. Thaib MR, Harjanto E, George YWH. Comparative study of the effectiveness of pethidine for prevention of post anesthtetic shivering in general anesthesia. Asean Otorhinolaryngology Head & Neck Surgery Journal 1999 ; 3:108 – 15.
15. Mathews S., Al Mulia A., Varghese PK, Radim K, Mumtaz S. Pethidine for
Postanesthetic shivering. Anaesthesia 2002;65 : 578 – 83.
16. Kramer TH. Opioids in anesthesia practice. In : Longnecker DE., Murphy FL (eds). Introduction to anesthesia. Philadelphia : W.B. Saunders Company,
1997 : 100.
17. Stoelting RK. Opioid agonist and antagonist. In : Stoelting RK.
Pharmacology and physiology in anesthetic practice. 3rd ed. Philadelphia :
JB Lippincott Company 1999 : 82 – 4.
18. Kranke. P, Eberhart. H.L. Pharmacological treatment of perioperative shivering. Anesth. Analg. 2002; 94: 453 – 60.
19. Candido KD, Collins VJ. Antagonist to narcortics. In : Collins VJ (ed).
Physiologic and pharmacologic bases of anesthesia. Baltimore : William & Wilkins, 1996 : 582 –3.
20. Stoelting RK. Alpha and beta adrenergic receptor antagonists. In : Stoelting RK. Pharmacology and physiology in anesthetic practice. 3rd ed. Philadelphia : JB Lippincott Company 1999 : 294 – 305.
21. Akinci. B, Basgul. E, Aypar. U. Pharmacological modulation of
shivering.Br. J. Anaesth. 1997: 613 – 7.
22. Miller.R.D. Anesthesia. 6th edition. Philadelphia: Churchill Livingstone, 2005. 240 – 4
23. Harun SR, Putra ST, Wiharta AS, Chair I. Uji klinis. Dalam : Sastroasmoro S, Ismael S, eds. Dasar-dasar metodologi penelitian klinis edisi 2. Jakarta : Sagung Seto, 2002 : 144 – 64.
24. Madiyono B, Moeslicjan S, Sastroasmoro S, Budiman I, Purwanto SH. Perkiraan besar sampel. Dalam : Sastroasmoro S, Ismael S, penyunting. Dasar-dasar metodologi penelitian klinis. Jakarta : Sagung Seto, 2002 : 260 - 9.
25. Sastroasmoro S. Pemilihan subyek penelitian. Dalam : Sastroasmoro S,
Ismael S, eds. Dasar-dasar metodologi penelitian klinis edisi 2. Jakarta : Sagung Seto, 2002 : 67 – 77.
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Published
2017-10-26
How to Cite
Kresnoadi, E., Rahman, H., & Affarah, W. S. (2017). EFEKTIVITAS PETIDIN 25 MG INTRAVENA UNTUK MENCEGAH MENGGIGIL PASCA ANESTESI UMUM. Jurnal Kedokteran, 2(3). https://doi.org/10.29303/jku.v2i3.67
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